Blaire O’Brien, OD, is originally from Oklahoma and came to the University of Missouri in St. Louis (UMSL) as part of the "3+4 program" with the Honors College of Optometry in 2000. She graduated in 2007 and joined Clarkson Eyecare in 2009 as the full-time doctor at the 94 Crossing location.

Dr. O’Brien has participated in a mission trip to Paraguay providing eye care to rural underserved areas. Recently she has reduced her schedule to part-time to spend more time with her family. She lives in the O’Fallon area with her husband and two girls and is a parishioner at St. Joseph Parish in Cottleville, MO. She enjoys spending time outdoors and hiking the local trails.